Research study on how well oral semaglutide works for weight loss in adults with excess body weight
EU CTIS ID: 2025-524626-18-00
What this study is testing
- Therapeutic confirmatory (Phase III)
A plain-language read of the study's public EU CTIS listing. The study team confirms the details.
Who can take part
You may be able to join if
- 1. Informed consent obtained before any study-related activities. Study-related activities are any procedures that are carried out as part of the study, including activities to determine suitability for the study.
- 2. Female or male (sex at birth).
- 3. Age 18 years or above at the time of signing the informed consent.
- 4. Body mass index (BMI) of a) ≥ 27.0 kg/m2 with the presence of at least one weight-related comorbidity including, but not limited to, hypertension, dyslipidaemia, obstructive sleep apnoea or CV disease OR b) ≥ 30.0 kg/m2
- 5. History of at least one self-reported unsuccessful dietary effort to lose body weight.
You likely can't join if
- 1. A self-reported change in body weight > 5 % within 90 days before screening irrespective of medical records
- 2. HbA1c ≥ 6.5% (48 mmol/mol) as measured by the central laboratory at screening
- 3. Treatment with any medication prescribed for the indication of obesity or weight management within 90 days before screening, OR any consistent use of GLP-1 receptor agonists, including medication with glucagon like peptide-1 receptor agonist (GLP-1 RA) activity like dual GLP-1/gastric inhibitory peptide RAs, or amylin analogues 00 before screening. Consistent use is defined as treatment 00.
The study team makes the final eligibility decision.
Where it's taking place
- United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18-64 years, 65+ years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from EU CTIS; the study team decides eligibility.