Clinical trial for Esophageal Cancer
Official title Total Intravenous Anesthesia and Recurrence Free Survival
ClinicalTrials.gov ID: NCT04513808
What this study is testing
What is Propofol-based total intravenous anesthesia?
Propofol-based total intravenous anesthesia is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for esophageal cancer.
Also referred to as Propofol.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The investigators propose to compare recurrence-free survival in patients having potentially curative (Stages 1-3) surgery for esophageal cancer who will be randomly assigned to propofol-based total intravenous anesthesia or sevoflurane-based balanced general anesthesia.
- Phase 3: a large, late-stage study
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 90
You may be able to join if
- Primary esophageal cancer without known extension beyond the esophagus. (i.e. believed to be Tumor Stage 1-3).
- Scheduled for potentially curative esophageal cancer surgery.
- Written informed consent, including willingness to be assigned by chance to intravenous versus volatile anesthesia.
You likely can't join if
- Previous surgery for esophageal cancer (except diagnostic biopsies) Age \ 85 years old.
- ASA Physical Status ≥4.
- Any contraindication to propofol or sevoflurane.
- Other cancer not believed by the attending surgeon to be in long-term remission.
- Systemic disease believed by the attending surgeon to present ≥25% two- year mortality.
The study team makes the final eligibility decision.
Where it's taking place
- Shanghai, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 90 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Shanghai, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.