Prevention trial for Acute Kidney Disease
Official title Demethylating Agent Azacitidine on Prevention of Acute Kidney Injury-chronic Kidney Disease Continuum
ClinicalTrials.gov ID: NCT05325099
What this study is testing
What is Azacitidine?
Azacitidine is an investigational medicine, given as an injection under the skin, being studied as a potential treatment for acute kidney disease.
Also referred to as Vidaza.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Acute kidney injury (AKI) is increasing worldwide in recent years and is a major risk factor of chronic kidney disease (CKD). AKI, acute kidney disease (AKD) and CKD form a continuum whereby initial kidney injury leads to ongoing renal injury and eventually end-stage renal disease if no effective treatment is applied.
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 20 and older
You may be able to join if
- Patient with cardiac surgery associated-AKI, stage 2 and stage 3
You likely can't join if
- Chronic kidney disease
- Decompensated heart failure (EF \< 45%)
- Liver cirrhosis, child B or C
- Acute infection
- Acute bleeding
- Long-term use of immunosuppressant other than azacitidine
See the full eligibility criteria
- Patient with cardiac surgery associated-AKI, stage 2 and stage 3
- Chronic kidney disease
- Decompensated heart failure (EF \< 45%)
- Liver cirrhosis, child B or C
- Acute infection
- Acute bleeding
- Long-term use of immunosuppressant other than azacitidine
- Patients with active cancer other than acute leukemia or myelodysplastic syndrome
- Leukopenia, anemia or thrombocytopenia
- Pregnancy
The study team makes the final eligibility decision.
Where it's taking place
- Taipei, Taiwan
Compensation & support
A stipend or payment for your time may be offered.
No amount is published here - ClinicalTrials.gov has no reliable field for payment or travel support. Ask the study team what's actually covered (payment for your time, travel, parking, or other study costs), and never join a trial for the compensation alone.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 20 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Taipei, Taiwan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.