Clinical trial for Parkinson's Disease
Official title Effect of Synbiotic as an Adjuvant Therapy in the Treatment of Parkinson's Disease
ClinicalTrials.gov ID: NCT05576818
What this study is testing
What is Lactobacillus acidophilus 10 billion colony forming unit (CFU) and prebiotic fibers?
Lactobacillus acidophilus 10 billion colony forming unit (CFU) and prebiotic fibers is an investigational medicine, given as an once-daily, being studied as a potential treatment for parkinson's disease.
Also referred to as Synbiotic.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study aims to investigate the possible efficacy and safety of synbiotic preparation of Lactobacillus acidophilus probiotic with prebiotic fibers as an adjuvant therapy in the treatment of Parkinson's disease
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 45 to 65
You may be able to join if
- Age between 45 and 65 years old
- Both sexes
- Patients with Parkinson's disease on dopamine replacement therapy
- Modified Hoehn and Yahr stage, MHY 1-4
You likely can't join if
- Patients who are currently using or used antibiotics therapy in the preceding month
- Patients who are currently using or used other probiotic products in the preceding two weeks
- Patients scheduled to undergo GIT surgery or those underwent GIT surgery
- Patients with Known allergy to probiotics
- Patients receiving artificial enteral or intravenous nutrition
- Patients with depression and/or psychosis
See the full eligibility criteria
- Age between 45 and 65 years old
- Both sexes
- Patients with Parkinson's disease on dopamine replacement therapy
- Modified Hoehn and Yahr stage, MHY 1-4
- Patients who are currently using or used antibiotics therapy in the preceding month
- Patients who are currently using or used other probiotic products in the preceding two weeks
- Patients scheduled to undergo GIT surgery or those underwent GIT surgery
- Patients with Known allergy to probiotics
- Patients receiving artificial enteral or intravenous nutrition
- Patients with depression and/or psychosis
- Patients taking antioxidant and/or anti-inflammatory medications
- Patients with Hyperthyroidism
- Patients with inflammatory condition and/or condition involving oxidative stress
- Smokers
- Modified Hoehn \& Yahr stage MHY 5
The study team makes the final eligibility decision.
Where it's taking place
- Tanta, El Gharbia, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 45 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Tanta, El Gharbia, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.