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Compares treatment options for Peripheral Arterial Disease
Official title High-intensity Intervals Versus Low-to-moderate-intensity Exercise Training in Patients With PAD
ClinicalTrials.gov ID: NCT05612945
What this study is testing
- What it's testing
- Supervised exercise training (SET) is considered among first-line therapies for patients with symptomatic lower extremity peripheral artery disease (PAD), combined with general cardiovascular risk management, lifestyle adaptation and pharmacological treatment. Although without clear consistency, the guidelines give recommendations in terms of claudication pain severity, SET volume, duration, and frequency.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adult patients with symptomatic PAD (Fontaine stage IIa/b);
- ABI ≤ 0.9 or drop by 20% following exercise treadmill test 1;
- TBI ≤ 0.6 if incompressible arteries (diabetes and renal insufficiency);
- Signed written informed consent form.
You likely can't join if
- Age \< 18;
- Unable to walk at 3.2 km/h on a treadmill (slope 0%) at least 300 m;
- Previous participate in SET programs ≤ 1 year;
- Prior leg/foot amputation;
- Contraindication to exercise
- Neurological and neuromuscular disorders and other comorbidities (orthopedic, rheumatologic) leading to gait abnormalities.
See the full eligibility criteria
- Adult patients with symptomatic PAD (Fontaine stage IIa/b);
- ABI ≤ 0.9 or drop by 20% following exercise treadmill test 1;
- TBI ≤ 0.6 if incompressible arteries (diabetes and renal insufficiency);
- Signed written informed consent form.
- Age \< 18;
- Unable to walk at 3.2 km/h on a treadmill (slope 0%) at least 300 m;
- Previous participate in SET programs ≤ 1 year;
- Prior leg/foot amputation;
- Contraindication to exercise
- Neurological and neuromuscular disorders and other comorbidities (orthopedic, rheumatologic) leading to gait abnormalities.
- Known Pregnancy
- Incapacity of discernment
The study team makes the final eligibility decision.
Where it's taking place
- Lausanne, Canton of Vaud, Switzerland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Lausanne, Canton of Vaud, Switzerland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.