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New treatment option for Mild Cognitive Impairment
Official title Causal Effect of Coenzyme Q10 Nutrition and Cognitive Dysfunction in the Metabolic Storm (Hyperglycemia and Sarcopenia) and Brain-derived Neurotrophic Factor
ClinicalTrials.gov ID: NCT06040905
What this study is testing
- What it's testing
- The aim of the study is to investigate the effect of coenzyme Q10 supplementation (150 mg/b.i.d, 300 mg/d, 12 weeks) on coenzyme Q10, glucose parameters, BDNF, myokines, and cognitive function in mild cognitive impairment (MCI) and Alzheimer's disease (AD) patients who combined with hyperglycemia but without sarcopenia, or with hyperglycemia and pre-sarcopenia.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 to 80
You may be able to join if
- Clinical diagnosis of mild cognitive impairment (MCI).
- Clinical diagnosis of Alzheimer's Disease.
- MCI and AD patients with hyperglycemia ( Fasting glucose \>=100 mg/dL).
- MCI and AD patients with pre-sarcopenia (low calf circumference, low hand grip, or low muscle endurance).
- Must be able to swallow tablets.
You likely can't join if
- Cancer patients.
- Severe heart, lung, liver, and kidney diseases.
- Severe disability or aphasia.
- Malnutrition (body weight changes \> 5% within one month).
- Using coenzyme Q10 supplements.
- Warfarin therapy.
The study team makes the final eligibility decision.
Where it's taking place
- Taichung, Taiwan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Taichung, Taiwan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.