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Official title Sleep Restriction and Parental History of Hypertension
ClinicalTrials.gov ID: NCT06482814
What this study is testing
- What it's testing
- The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individuals whose parents have normal blood pressure.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 35. Healthy volunteers may be eligible.
You may be able to join if
- Healthy adults aged 18-35 years
- Absence of any significant medical or psychiatric disease (as per the investigators' judgment)
- Nonsmoker
- Nonpregnant
- History of normal sleep duration (reported average sleep duration between 7-9 hours/night and no habitual napping)
You likely can't join if
- Age \ 35 years
- Body mass index \<18.5 or ≥30 kg/m2
- Pregnant or lactating
- Unable to determine history of HTN in participant's biological parents or subject being adopted
- Use of tobacco, vaping, marijuana products or other drugs
- Excessive caffeine consumption (\>400 mg/day)
See the full eligibility criteria
- Healthy adults aged 18-35 years
- Absence of any significant medical or psychiatric disease (as per the investigators' judgment)
- Nonsmoker
- Nonpregnant
- History of normal sleep duration (reported average sleep duration between 7-9 hours/night and no habitual napping)
- Hypertension status information available for both biological parents
- Ability to understand study procedures and to comply with them for the entire length of the study
- Ability to understand English and provide informed consent
- Age \ 35 years
- Body mass index \<18.5 or ≥30 kg/m2
- Pregnant or lactating
- Unable to determine history of HTN in participant's biological parents or subject being adopted
- Use of tobacco, vaping, marijuana products or other drugs
- Excessive caffeine consumption (\>400 mg/day)
- Excessive alcohol consumption (\>7 drinks/week for women, \>14 drinks/week for men)
- Office SBP/DBP ≥130/80 mmHg
- Daytime ambulatory SBP/DBP ≥130/80 mmHg
- Fasting glucose ≥126 mg/dl
- Glomerular filtration rate \<60 mL/min/BSA
- History of significant medical or psychiatric disorders (as per the investigators' judgment)
- Regular use of prescription medications other than contraceptives
- Use of melatonin supplements or any other over-the-counter sleep aid
- Moderate-to-severe sleep disordered breathing (apnea/hypopnea index, AHI ≥15) or mild sleep disordered breathing (AHI 5-15) with daytime sleepiness (Epworth Sleepiness Scale \>10)
- Moderate-to-severe insomnia (Insomnia Severity Index \>14)
- Restless leg syndrome (as per the Cambridge-Hopkins questionnaire)
- Excessive daytime sleepiness (Epworth Sleepiness Scale \>15)
- Extreme chronotype (Morningness-Eveningness Questionnaire \>69 or \<31)
- Night shift work
- Ongoing participation in other research studies (as per the investigators' judgment)
- Any other medical, geographic, or social factor making study participation impractical
- Not English-speaking and/or inability to provide informed consent
- Exclusionary for blood draws: hemoglobin \<11.6 g/dL in women / \<13.2 g/dL in men; participants with measured hemoglobin levels below these thresholds will be allowed to continue participate in study tests and...
The study team makes the final eligibility decision.
Where it's taking place
- Rochester, Minnesota, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 35 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Rochester, Minnesota, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.