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New treatment option for Degenerative Joint Disease
Official title Hyaluronic Acid and Adelmidrol (Hyadrol®) in Patients With Degenerative Joint Disease
ClinicalTrials.gov ID: NCT06506656
What this study is testing
- What it's testing
- Osteoarthritis is a major cause of chronic musculoskeletal pain. Behind this disorder there is a process of chronic neuroinflammation due to the overactivation of mast cells at the tissue level.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 and older
You may be able to join if
- age ≥ 40 years;
- both genders;
- diagnosis of stage II-III coxarthrosis or rhizoarthrosis according to radiological classification (Kellgren and Lawrence or modified Eaton-Littler...
- pain intensity ≥ 5 on NRS;
- wash-out for at least two weeks from anti-inflammatory drugs before enrollment;
You likely can't join if
- age \< 40 years;
- presence of concomitant inflammatory systemic pathologies (e.g.: rheumatoid arthritis, etc.);
- severe and progressive clinical conditions,
- NSAIDs therapy in the 2 weeks prior to enrollment;
- corticosteroid therapy in the 3 months prior to enrollment;
- chondroprotectors intake in the 6 months prior to enrollment;
See the full eligibility criteria
- age ≥ 40 years;
- both genders;
- diagnosis of stage II-III coxarthrosis or rhizoarthrosis according to radiological classification (Kellgren and Lawrence or modified Eaton-Littler criteria respectively)
- pain intensity ≥ 5 on NRS;
- wash-out for at least two weeks from anti-inflammatory drugs before enrollment;
- compliant patients;
- signed informed consent.
- age \< 40 years;
- presence of concomitant inflammatory systemic pathologies (e.g.: rheumatoid arthritis, etc.);
- severe and progressive clinical conditions,
- NSAIDs therapy in the 2 weeks prior to enrollment;
- corticosteroid therapy in the 3 months prior to enrollment;
- chondroprotectors intake in the 6 months prior to enrollment;
- arthroscopic procedures or intra-articular visco-supplementation in the 6 months prior to enrollment;
- presence of cognitive impairment;
- ongoing rehabilitation and/or physiotherapy;
- allergy or hypersensitivity to the study treatment;
- pregnant and/or lactating female people;
- not compliant patients;
- denied informed consent.
The study team makes the final eligibility decision.
Where it's taking place
- Roma, Italy
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Roma, Italy. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.