Clinical trial for Fibromyalgia
Official title Relationships of Affect and Neuroinflammation With Clinical Pain in Veterans With Fibromyalgia
ClinicalTrials.gov ID: NCT06574165
What this study is testing
- What it's testing
- The study aims to find out how emotional traits and inflammation relate to pain in veterans with fibromyalgia and to design a veteran‑focused exercise program.
- Who it's for
- Veterans who have been diagnosed with fibromyalgia.
- What's involved
- Participants will undergo assessments of pain, mood, and inflammation, and will help shape an exercise program for managing their condition.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 19 to 85. Healthy volunteers may be eligible.
You may be able to join if
- for Veterans living with FM:
- (FM) Age 19 years or older
- Widespread pain index (WPI) 7 and symptom severity scale (SSS) score 5 OR WPI 4-6 and SSS score 9
- Generalized pain, defined as pain in at least 4 of 5 regions, is present
- Symptoms have been present at a similar level for at least 3 months
You likely can't join if
- Exclusion Criteria for Veterans living with FM:
- Neurological disorder
- Body mass index \> 40
- Chronic kidney disease
- Severe cardiac condition (chronic heart failure, stenosis, history of cardiac arrest, defibrillator, angina)
- Ischemic heart disease
See the full eligibility criteria
- for Veterans living with FM:
- (FM) Age 19 years or older
- Widespread pain index (WPI) 7 and symptom severity scale (SSS) score 5 OR WPI 4-6 and SSS score 9
- Generalized pain, defined as pain in at least 4 of 5 regions, is present
- Symptoms have been present at a similar level for at least 3 months
- A diagnosis of FM is valid irrespective of other diagnoses. A diagnosis of FM does not exclude the presence of other clinically important illnesses
- PTSD Checklist-Stressor-Specific Version 1 re-experiencing (intrusion) symptom, 3 avoidance (numbing) symptoms, and 2 hyperarousal symptoms, each present at the level of moderate or higher during the past month, and if...
- Age-matched to participant with FM
- Exclusion Criteria for Veterans living with FM:
- Neurological disorder
- Body mass index \> 40
- Chronic kidney disease
- Severe cardiac condition (chronic heart failure, stenosis, history of cardiac arrest, defibrillator, angina)
- Ischemic heart disease
- 90 days of daily opioid use
- Beta-blocker
- Inability to consent for study participation (9) Significant cognitive impairment, defined as a known diagnosis of dementia (10) MRI contraindications (11) Pregnancy Exclusion Criteria for Veterans living without FM:
- Active use of medications affecting pain responses
- Neurological disorder
- Body mass index \> 40
- MRI contraindications
- Pregnancy
The study team makes the final eligibility decision.
Where it's taking place
- Birmingham, Alabama, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 19 years to 85 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Birmingham, Alabama, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.