Clinical trial for Myeloid Leukemia, Acute
Official title Integrative "Omics" Approaches for Leukemia Target Identification and Matched Therapeutic Intervention
ClinicalTrials.gov ID: NCT06626893
What this study is testing
What is Functional tests?
Functional tests is an investigational medicine, being studied as a potential treatment for myeloid leukemia, acute.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this clinical trial is to use multiple "omics" sciences to more thoroughly investigate Acute Recurrent/Refractory Leukemias (LA R/R) after conventional therapy in order to identify new targets and/or therapeutic approaches, in patients with a diagnosis of Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia/ Lymphoblastic Lymphoma B(ALL-B), Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma T (ALL-T), Acute Biphenotypic Leukemia/II as defined by WHO( World Health Organization) 2016, relapsed or refractory after at least one line of therapy. The main question that the trial aims to answer is: "Can molecules with known biological activity be active and represent possible new therapeutic strategies in relapsed/refractory Acute Leukemias on the basis of response profiles identified through the integration of next-generation chemogenomic and functional analyses?
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Patients to be enrolled in the study must have a diagnosis of AML, B ALL/LBL, T ALL/LBL, MPAL/AUL as described by WHO 2016 classification and must...
- Ages Eligible for Study: over 18years
- Patients must have greater than 5% blasts in the bone marrow with or without extramedullary disease
- Patients with must have recurrent disease, documented by clinical or radiographic criteria, as well as histologic verification of the malignancy at...
- Patients may be enrolled on study regardless of the timing of prior I therapy
See the full eligibility criteria
- Patients to be enrolled in the study must have a diagnosis of AML, B ALL/LBL, T ALL/LBL, MPAL/AUL as described by WHO 2016 classification and must complained relapsed or refractory disease after at least one line of...
- Ages Eligible for Study: over 18years
- Patients must have greater than 5% blasts in the bone marrow with or without extramedullary disease
- Patients with must have recurrent disease, documented by clinical or radiographic criteria, as well as histologic verification of the malignancy at original diagnosis
- Patients may be enrolled on study regardless of the timing of prior I therapy
- Patients must be capable of understanding the investigational nature and the objectives of the study. All patients must sign a written informed consent.
The study team makes the final eligibility decision.
Where it's taking place
- Meldola, Forlì-Cesena, Italy
- Bologna, Italy
- Ferrara, Italy
- Parma, Italy
- Piacenza, Italy
- Ravenna, Italy
- Reggio Emilia, Italy
- Rimini, Italy
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Meldola, Forlì-Cesena, Italy; Bologna, Italy; Ferrara, Italy; Parma, Italy; Piacenza, Italy; Ravenna, Italy and 2 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.