Clinical trial for Knee Osteoarthrosis
Official title Use of Extracellular Vesicles (EV) for Knee Osteoarthrosis
ClinicalTrials.gov ID: NCT06937528
What this study is testing
What is Extracellular vesicles?
Extracellular vesicles is an investigational medicine, given as an injectable medicine, being studied as a potential treatment for knee osteoarthrosis.
Also referred to as EV.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Extracellular vesicles (EV) will be injected in patients diagnosed with Knee osteoarthrosis
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 42 to 75
You may be able to join if
- Severe KOA stage III or IV by Laurance \& Kellgren staging as judged by Posterioranterior (PA) Xray of the knee joint.
- Willing to participate by signing the informed consent
You likely can't join if
- Sublaxation beyond 20 degrees of the bones of the knee joint
- Oral anticoagulants or heparin therapy
- Heart failure or arrhythmia
- Body Mass Index \> 35
- Uncontrolled Diabetes Mellitus.
- Evidence of Infectious Diseases.
See the full eligibility criteria
- Severe KOA stage III or IV by Laurance \& Kellgren staging as judged by Posterioranterior (PA) Xray of the knee joint.
- Willing to participate by signing the informed consent
- Sublaxation beyond 20 degrees of the bones of the knee joint
- Oral anticoagulants or heparin therapy
- Heart failure or arrhythmia
- Body Mass Index \> 35
- Uncontrolled Diabetes Mellitus.
- Evidence of Infectious Diseases.
- Active infection
- Malignancy
- Pregnancy
- Anemia less than 11g/dl or thrombocytopenia less than 100,000 or leucopenia less than 3000.
- Unreliable patients
- Non-resident in Jordan
The study team makes the final eligibility decision.
Where it's taking place
- Amman, Jordan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 42 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Amman, Jordan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.