Clinical trial for Essential Tremor
Official title Simultaneous Bilateral Radiofrequency Thalamotomy for Medication-Refractory Essential Tremor
ClinicalTrials.gov ID: NCT07066358
What this study is testing
- What it's testing
- This study aims to evaluate the safety and effectiveness of simultaneous bilateral radiofrequency thalamotomy for patients with medication-refractory essential tremor (ET). Essential tremor is a common neurological condition that causes involuntary shaking, often affecting the hands and interfering with daily activities such as writing, eating, or using tools.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 20 to 70
You may be able to join if
- Adults aged 20 to 70 years.
- Diagnosis of essential tremor by a neurologist or neurosurgeon specializing in movement disorders.
- Refractory to standard pharmacological therapy (e.g., propranolol, primidone, benzodiazepines, or alprenolol).
- Mini-Mental State Examination (MMSE) score ≥ 27.
- Able to undergo MRI.
You likely can't join if
- History or evidence of bleeding tendency.
- MRI contraindications (e.g., metallic implants, severe claustrophobia).
- Presence of intracranial pathology on preoperative MRI that would interfere with surgery.
- Pregnant or breastfeeding individuals.
- Any other condition that the principal investigator deems inappropriate for study participation.
See the full eligibility criteria
- Adults aged 20 to 70 years.
- Diagnosis of essential tremor by a neurologist or neurosurgeon specializing in movement disorders.
- Refractory to standard pharmacological therapy (e.g., propranolol, primidone, benzodiazepines, or alprenolol).
- Mini-Mental State Examination (MMSE) score ≥ 27.
- Able to undergo MRI.
- Provided written informed consent for participation in the study.
- History or evidence of bleeding tendency.
- MRI contraindications (e.g., metallic implants, severe claustrophobia).
- Presence of intracranial pathology on preoperative MRI that would interfere with surgery.
- Pregnant or breastfeeding individuals.
- Any other condition that the principal investigator deems inappropriate for study participation.
The study team makes the final eligibility decision.
Where it's taking place
- Shinjuku-Ku, Tokyo, Japan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 20 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Shinjuku-Ku, Tokyo, Japan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.