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Compares treatment options for Knee Osteoarthritis
Official title ACB With S-ESPB Versus ACB With iPACK for Knee Arthroplasty
ClinicalTrials.gov ID: NCT07288970
What this study is testing
- What it's testing
- This study will compare two regional anesthesia strategies for pain management after total knee arthroplasty in adults. Both strategies use an adductor canal block (ACB) to provide analgesia while preserving quadriceps muscle strength.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 65 to 100
You may be able to join if
- Age 65 years or older
- Scheduled for elective unilateral total knee arthroplasty under spinal or general anesthesia
- ASA physical status I-III
- Planned use of regional anesthesia with an adductor canal block as part of multimodal analgesia
- Ability to communicate pain intensity using the NRS scale
You likely can't join if
- Refusal or inability to provide informed consent
- Allergy, intolerance, or contraindication to local anesthetics (ropivacaine)
- Pre-existing significant neurological deficit or neuropathy in the operative limb
- Coagulopathy or anticoagulation that contraindicates peripheral nerve blocks (e.g., INR \>1.5, platelets \<100,000/µL, or therapeutic anticoagulation...
- Infection at or near the planned needle insertion sites
- Severe hepatic or renal impairment
See the full eligibility criteria
- Age 65 years or older
- Scheduled for elective unilateral total knee arthroplasty under spinal or general anesthesia
- ASA physical status I-III
- Planned use of regional anesthesia with an adductor canal block as part of multimodal analgesia
- Ability to communicate pain intensity using the NRS scale
- Written informed consent obtained from the patient
- Refusal or inability to provide informed consent
- Allergy, intolerance, or contraindication to local anesthetics (ropivacaine)
- Pre-existing significant neurological deficit or neuropathy in the operative limb
- Coagulopathy or anticoagulation that contraindicates peripheral nerve blocks (e.g., INR \>1.5, platelets \<100,000/µL, or therapeutic anticoagulation that cannot be safely paused)
- Infection at or near the planned needle insertion sites
- Severe hepatic or renal impairment
- Chronic opioid therapy (\>30 days of daily opioid use before surgery)
- Cognitive impairment or delirium preventing reliable pain assessment BMI \> 40 kg/m² (optional - if chcesz ograniczyć ze względu na trudność USG)
- Previous knee arthroplasty on the same side or revision TKA (jeśli chcesz tylko primary TKA)
- Pregnancy or breastfeeding
- Participation in another treatment clinical trial within 30 days
The study team makes the final eligibility decision.
Where it's taking place
- Poznan, Poland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65 years to 100 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Poznan, Poland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.