Clinical trial for Amyotrophic Lateral Sclerosis
Official title LONgitudinal and Integrated Evaluation of Biomarkers in reLation to phenotYpe in ALS
ClinicalTrials.gov ID: NCT07312240
What this study is testing
- What it's testing
- Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive degeneration of upper and lower motor neurons, leading to paralysis and death. Despite its uniformly fatal outcome, ALS shows marked clinical heterogeneity with respect to phenotype, progression rate, cognitive involvement, and survival.
- Time commitment: about 36 months
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older. Healthy volunteers may be eligible.
You may be able to join if
- ALS patients:
- diagnosis of Amyotrophic Lateral Sclerosis (ALS);
- age ≥18 y;
- feasibility of lumbar puncture (LP);
- informed consent.
You likely can't join if
- ALS patients:
- severe medical comorbidities;
- recent traumatic, inflammatory, vascular, or neoplastic Central Nervous System disease; contraindications to LP. Inclusion Criteria Controls:
- age ≥18 y;
- individuals undergoing LP for neurological symptoms;
- no evidence of nervous system pathology;
See the full eligibility criteria
- ALS patients:
- diagnosis of Amyotrophic Lateral Sclerosis (ALS);
- age ≥18 y;
- feasibility of lumbar puncture (LP);
- informed consent.
- ALS patients:
- severe medical comorbidities;
- recent traumatic, inflammatory, vascular, or neoplastic Central Nervous System disease; contraindications to LP. Inclusion Criteria Controls:
- age ≥18 y;
- individuals undergoing LP for neurological symptoms;
- no evidence of nervous system pathology;
- informed consent.
The study team makes the final eligibility decision.
Where it's taking place
- Milan, Lombardy, Italy
Compensation & support
This study's listing mentions compensation or reimbursement.
No amount is published here - ClinicalTrials.gov has no reliable field for payment or travel support. Ask the study team what's actually covered (payment for your time, travel, parking, or other study costs), and never join a trial for the compensation alone.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 36 months per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Milan, Lombardy, Italy. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.