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New treatment option for Aerobic Exercise
Official title Effects of an Aerobic Exercise Program on Cardiovascular Risk in Patients With Chronic Kidney Disease or Rheumatoid Arthritis
ClinicalTrials.gov ID: NCT07469540
What this study is testing
- What it's testing
- The goal of this clinical trial is to determine whether an aerobic exercise program can reduce cardiovascular risk in patients with systemic inflammation, such as those with rheumatoid arthritis and chronic kidney disease. The main questions this study aims to address are: Does an individualized aerobic exercise program reduce cardiovascular risk, as assessed arterial stiffness and endothelial function ?
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 and older
You may be able to join if
- Diagnosis of Chronic Kidney Disease (CKD) or Rheumatoid Arthritis (RA), with no other risk factors related to the disease.
- Having a glomerular filtration rate between 45 and 20 ml/min/1.73 m², corresponding to stages III and IV not on dialysis for patients with CKD ; or...
- Have a medical certificate stating that there are no adverse reactions to physical activity.
- Affiliation with a French social security scheme or beneficiary of such a scheme.
You likely can't join if
- Unstabilised corticosteroid therapy and/or \>10mg prednisone/day
- Uncontrolled high blood pressure
- Pregnant women
- Impaired higher functions making it impossible to understand and adhere to an aerobic exercise program
- Inability to perform physical exercise, regardless of the cause (neurological, central or peripheral, cardiovascular or respiratory, or...
- Legal incapacity or limited legal capacity
See the full eligibility criteria
- Diagnosis of Chronic Kidney Disease (CKD) or Rheumatoid Arthritis (RA), with no other risk factors related to the disease.
- Having a glomerular filtration rate between 45 and 20 ml/min/1.73 m², corresponding to stages III and IV not on dialysis for patients with CKD ; or have a DAS 28 score ≥ 2.6 points for patients with RA.
- Have a medical certificate stating that there are no adverse reactions to physical activity.
- Affiliation with a French social security scheme or beneficiary of such a scheme.
- Unstabilised corticosteroid therapy and/or \>10mg prednisone/day
- Uncontrolled high blood pressure
- Pregnant women
- Impaired higher functions making it impossible to understand and adhere to an aerobic exercise program
- Inability to perform physical exercise, regardless of the cause (neurological, central or peripheral, cardiovascular or respiratory, or musculoskeletal)
- Legal incapacity or limited legal capacity
- Subject unlikely to cooperate with the study and/or low cooperation anticipated by the investigator
- Subject without health insurance
- Subject is in the exclusion period of another study involving human people that may interfere with the results of this study, particularly by affecting inflammatory status and the cardiovascular system.
The study team makes the final eligibility decision.
Where it's taking place
- Besançon, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Besançon, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.