Trial comparing treatments for Hypercholesterolaemia
Official title A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With Laroprovstat, Rosuvastatin and Placebo on LDL-C in LLT-naïve Patients.
ClinicalTrials.gov ID: NCT07619131
What this study is testing
What is Laroprovstat?
Laroprovstat is an investigational medicine, given as an once-daily pill taken by mouth, being studied as a potential treatment for hypercholesterolaemia.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This is a study to evaluate the effect on LDL-C and the safety and tolerability of FDC laroprovstat/rosuvastatin in LLT-naïve patients. Laroprovstat is a small molecule that reduces the amount of LDL-C in the blood.
- Phase 3: a large, late-stage study
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 130
You may be able to join if
- Participant must be ≥ 18 years of age
- Participants with no clinical history of atherosclerotic cardiovascular disease (ASCVD) and a 10-year ASCVD risk estimated as low
- Participants who have not received any LLT in the 3 months prior to screening
You likely can't join if
- Asian origin.
- Statin intolerance
- Uncontrolled severe hypertension
- Uncontrolled type 2 diabetes mellitus
- Inadequately treated hypothyroidism
The study team makes the final eligibility decision.
Where it's taking place
- Dothan, Alabama, United States
- Chandler, Arizona, United States
- Phoenix, Arizona, United States
- Huntington Beach, California, United States
- Loma Linda, California, United States
- Lomita, California, United States
- Long Beach, California, United States
- San Dimas, California, United States
- Arvada, Colorado, United States
- Colorado Springs, Colorado, United States
- Waterbury, Connecticut, United States
- Clearwater, Florida, United States
- DeLand, Florida, United States
- Hollywood, Florida, United States
- Jacksonville, Florida, United States
- Lakeland, Florida, United States
- Miami Lakes, Florida, United States
- Ocoee, Florida, United States
- Plantation, Florida, United States
- Port Orange, Florida, United States
+ 113 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 130 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Dothan, Alabama, United States; Chandler, Arizona, United States; Phoenix, Arizona, United States; Huntington Beach, California, United States; Loma Linda, California, United States; Lomita, California, United States and 127 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.