Healthy study: MR Imaging Techniques -
Official title New Heart Imaging Techniques to Evaluate Possible Heart Disease
ClinicalTrials.gov ID: NCT01399385
What this study is testing
- What it's testing
- The study aims to find out if new MRI techniques can accurately show heart and blood vessel health without using radiation.
- Who it's for
- The study is looking for adults 18 or older who have or may have heart disease, or healthy volunteers.
- What's involved
- Participants will have a physical exam, blood tests, an x-ray of their blood vessels, and up to five MRI scans. They may also have a CT scan to double-check the MRI results.
- Time commitment
- The study involves multiple visits for imaging and tests, but the total duration is not specified.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 100. Healthy volunteers may be eligible.
You may be able to join if
- 1. people with or without history of cardiovascular diseases and with various degrees of cardiovascular risk factor.
- Subject must be willing to participate in the protocol.
- Subject age greater than 18 years old.
- Subject must be able to provide informed consent.
- Subject must be clinically stable and be able to come to the Clinical Center to participate in the study.
You likely can't join if
- Implanted cardiac pacemaker or defibrillator
- Cochlear Implants
- Ocular foreign body (e.g. metal shavings)
- Embedded shrapnel fragments
- Central nervous system aneurysm clips
- Implanted neural stimulator
See the full eligibility criteria
- 1. people with or without history of cardiovascular diseases and with various degrees of cardiovascular risk factor.
- Subject must be willing to participate in the protocol.
- Subject age greater than 18 years old.
- Subject must be able to provide informed consent.
- Subject must be clinically stable and be able to come to the Clinical Center to participate in the study.
- Implanted cardiac pacemaker or defibrillator
- Cochlear Implants
- Ocular foreign body (e.g. metal shavings)
- Embedded shrapnel fragments
- Central nervous system aneurysm clips
- Implanted neural stimulator
- Medical infusion pumps
- Any implanted device that is incompatible with MRI.
- Unsatisfactory performance status as judged by the referring physician such that the subject could not tolerate an MRI scan.
- people requiring sedation for MRI studies.
- people with a condition precluding entry into the scanner (e.g. morbid obesity, claustrophobia, etc.).
- Pregnant or lactating women.
- people with severe back-pain or motion disorders who will be unable to tolerate supine positioning within the MRI scanner and hold still for the duration of the examination.
- History of allergic reaction to gadolinium contrast agents despite the use of premeditation with an anti-histaminic and cortisone.
- Creatinine value \> 1.4 mg/dl
- History of multiple myeloma
- Use of metformin-containing products less than 24 hrs prior to contrast administration
- History of allergic reaction to CTA contrast agents despite the use of pre- medication with an anti-histaminic and cortisone.
- Asthma
- Active bronchospasm
- Moderate or severe COPD
- 2nd or 3rd degree AV block
- Decompensated cardiac failure
- Allergy to beta blockers
- Systolic blood pressure \< 100 mm Hg
- Severe aortic stenosis
- Hypertrophic cardiomyopathy
- Inferior myocardial infarction with right ventricular involvement
- Cardiac tamponade
- Constrictive pericarditis
- Severe hypotension (systolic BP \<90 mmHg)
- Uncorrected hypovolemia
- Raised intracranial pressure
- Glaucoma
- Severe anemia
- Concomitant use of phosphodiesterase-5 inhibitors (sildenafil-Viagra, tadalifil-Cialis, verdenafil-Levitra)
- History of hypersensitivity to nitroglycerin
The study team makes the final eligibility decision.
Where it is enrolling
- Bethesda, Maryland, United States
Compensation & support
A stipend or payment for your time may be offered.
No amount is published here because ClinicalTrials.gov has no reliable field for payment or travel support. Ask the study team what's actually covered (payment for your time, travel, parking, or other study costs), and never join a trial for the compensation alone.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team, so confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 100 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Bethesda, Maryland, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.