Clinical trial for Unruptured Brain Arteriovenous Malformation
Official title Treatment of Brain AVMs (TOBAS) Study
ClinicalTrials.gov ID: NCT02098252
What this study is testing
- What it's testing
- The study wants to see if medical care alone or with surgery/radiation can lower the chance of death or serious stroke by about 15% over 10 years for unruptured AVMs, and if adding a pre‑treatment embolization can improve surgery or radiation outcomes by 10% and reduce treatment failures by half.
- Who it's for
- It is looking for adults who have a brain arteriovenous malformation, whether it has bled or not.
- What's involved
- Participants may receive medical care, surgery, radiation, or a combination, and some may have a small procedure called embolization before surgery or radiation. They will have regular visits and tests to monitor their condition.
- Time commitment
- The study lasts up to 10 years, with scheduled visits and tests throughout that period.
- Time commitment: about 10 years
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 5 and older
You may be able to join if
- Any patient with a brain AVM
You likely can't join if
- Hemorrhagic presentation with mass effect requiring surgical management.
The study team makes the final eligibility decision.
Where it is enrolling
- Jacksonville, Florida, United States
- Boston, Massachusetts, United States
- Albuquerque, New Mexico, United States
- Fortaleza, Brazil
- São Paulo, Brazil
- Edmonton, Alberta, Canada
- Montreal, Quebec, Canada
- Santiago, Chile
- Bucaramanga, Colombia
- Brest, Brittany Region, France
- Besançon, France
- Bordeaux, France
- Caen, France
- Clermont-Ferrand, France
- Dijon, France
- Le Kremlin-Bicêtre, France
- Limoges, France
- Lyon, France
- Marseille, France
- Montpellier, France
+ 8 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The study runs about 10 years per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 5 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Jacksonville, Florida, United States; Boston, Massachusetts, United States; Albuquerque, New Mexico, United States; Fortaleza, Brazil; São Paulo, Brazil; Edmonton, Alberta, Canada and 22 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.