Clinical trial for Shock
Official title Vasoactive Drugs in Intensive Care Unit
ClinicalTrials.gov ID: NCT02118467
What this study is testing
What is Norepinephrine?
An investigational drug being studied as a potential treatment for shock in ICU patients. It is designed to raise blood pressure by stimulating alpha‑adrenergic receptors, causing blood‑vessel constriction.
Also referred to as Levophed.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether phenylephrine and vasopressin reduce fast heart rhythms in ICU patients with shock that does not improve with fluids. It compares these drugs to norepinephrine and epinephrine.
- Who it's for
- You may be able to join if you are an adult in the ICU with shock that does not respond to IV fluids.
- What's involved
- You will receive one of two drug combinations while in the ICU. The study team will monitor your heart rhythm and other vital signs during your stay.
- Time commitment
- The study lasts as long as you stay in the ICU, with regular checks by the research team during your treatment.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age greater than or equal to 18 years old
- Requirement for vasoactive drugs via a central venous catheter for the treatment of shock.
You likely can't join if
- Cardiopulmonary arrest
- Pregnancy
- Severe right heart failure
The study team makes the final eligibility decision.
Where it is enrolling
- Chicago, Illinois, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Chicago, Illinois, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.