Influenza study: Influenza
Official title Influenza Immunization in Adults Over Age 75
ClinicalTrials.gov ID: NCT02200276
What this study is testing
What is Influenza?
An investigational study of the flu shot being studied to see how older adults' immune systems respond to the influenza vaccine. The vaccine is designed to stimulate the immune system to produce antibodies against influenza viruses.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study wants to see how the immune system of people over 75 reacts to the flu vaccine and whether a common virus called cytomegalovirus changes that response.
- Who it's for
- Adults age 75 or older, whether healthy or frail, who can give consent.
- What's involved
- You will get a flu shot, have a few short visits for consent, medical history, vital signs, walking speed, grip strength, questionnaires, and urine and blood samples. Follow‑up visits include more blood draws and health surveys, plus weekly phone calls during flu season.
- Time commitment
- The study lasts about 4 weeks with visits at the start, 7 days, and 4 weeks after the shot, plus weekly phone check‑ins.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 75 and older. Healthy volunteers may be eligible.
You may be able to join if
- Adults over age 75 years
You likely can't join if
- Allergies to egg or vaccine
- Active malignancies
- On radiation or chemotherapy
- Active systemic inflammatory diseases including rheumatoid arthritis, Crohn's disease, and ulcerative colitis
- Acute exacerbation of chronic cardiopulmonary conditions including decompensated CHF or COPD
- Taking oral steroids (such as prednisone) or immune modulating drugs (such as methotrexate).
See the full eligibility criteria
- Adults over age 75 years
- Allergies to egg or vaccine
- Active malignancies
- On radiation or chemotherapy
- Active systemic inflammatory diseases including rheumatoid arthritis, Crohn's disease, and ulcerative colitis
- Acute exacerbation of chronic cardiopulmonary conditions including decompensated CHF or COPD
- Taking oral steroids (such as prednisone) or immune modulating drugs (such as methotrexate).
- Lacking the capacity to consent (individuals who do not understand what Flu shot is or need someone else to decide if s/he should get the Flu shot)
The study team makes the final eligibility decision.
Where it is enrolling
- Baltimore, Maryland, United States
Compensation & support
A stipend or payment for your time may be offered.
No amount is published here because ClinicalTrials.gov has no reliable field for payment or travel support. Ask the study team what's actually covered (payment for your time, travel, parking, or other study costs), and never join a trial for the compensation alone.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team, so confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 75 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Baltimore, Maryland, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.