Sleep Apnea study: Trazodone
Official title Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury
ClinicalTrials.gov ID: NCT02922894
What this study is testing
What is Trazodone?
an investigational oral medication being studied as a potential treatment for sleep apnea in people with chronic cervical spinal cord injury is designed to modulate serotonin activity by acting as a serotonin antagonist and reuptake inhibitor, which may influence breathing control during sleep
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether new therapies can improve sleep breathing problems in people with chronic cervical spinal cord injury.
- Who it's for
- You may be able to join if you have a neck spinal cord injury for more than six months and have sleep apnea.
- What's involved
- You will receive a treatment aimed at sleep breathing problems and attend study visits for check‑ups.
- Phase 4: studies an already-approved treatment
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 89. Healthy volunteers may be eligible.
You may be able to join if
- healthy adults between the ages of 18 - 89
- chronic spinal cord injury patients (T6 and above), \> 3 months since injury and not on mechanical ventilation, and have not received mechanical...
You likely can't join if
- people ≤ 17 yrs old
- Pregnant and lactating females
- History of head trauma that resulted in neurological symptoms or loss of consciousness
- advanced heart, lung, metabolic, liver or chronic kidney disease.
- severe obstructive or restrictive respiratory defect by PFTs or history of tracheostomy
- extreme obesity defined for this protocol as BMI ≥ 40 kg/m2 (to avoid the effect of morbid obesity on ventilation).
The study team makes the final eligibility decision.
Where it is enrolling
- Detroit, Michigan, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 89 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Detroit, Michigan, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.