Clinical trial for Methamphetamine Abuse
Official title rTMS for Craving in Methamphetamine Use Disorder
ClinicalTrials.gov ID: NCT03470480
What this study is testing
- What it's testing
- This study aims to find out if a specific type of brain stimulation can help lower the urge to use methamphetamine when people see pictures related to the drug.
- Who it's for
- The study is looking for adults who have a history of methamphetamine use and have recently stopped using the drug.
- What's involved
- Participants will receive daily brain stimulation treatments for two weeks, followed by weekly sessions for one month. Before each session, they will look at pictures and rate their cravings, and provide urine samples to check for drug use.
- Time commitment
- The study involves daily visits for two weeks, weekly visits for one month, and a phone call six months after treatment ends.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- people must use at least 0.5 g per day at least 5 days per week and have a minimum 12-month history of METH abuse.
- people must meet DSM V diagnosis for methamphetamine use disorder.
- people must have a minimum 4-week period of detoxification and a desire to stop using methamphetamine.
You likely can't join if
- Present or past history of neurological disorder
- The present history of a DSM IV Axis I or DSM V primary psychiatric disease (apart from MUD and depressive symptoms defined as a Hamilton Depression...
- Scores on the Hamilton Depression Scale \> 8, possibly indicating clinical depression
- No current abuse of drugs other than methamphetamine (except nicotine).
- Individuals meeting criteria for cannabis use disorder or alcohol use disorder
- Medical illness that can affect brain function
See the full eligibility criteria
- people must use at least 0.5 g per day at least 5 days per week and have a minimum 12-month history of METH abuse.
- people must meet DSM V diagnosis for methamphetamine use disorder.
- people must have a minimum 4-week period of detoxification and a desire to stop using methamphetamine.
- Present or past history of neurological disorder
- The present history of a DSM IV Axis I or DSM V primary psychiatric disease (apart from MUD and depressive symptoms defined as a Hamilton Depression Scale Score \< 7 ("normal"))
- Scores on the Hamilton Depression Scale \> 8, possibly indicating clinical depression
- No current abuse of drugs other than methamphetamine (except nicotine). Urine-screening tests for psychoactive drugs will be performed to corroborate the lack of drug use.
- Individuals meeting criteria for cannabis use disorder or alcohol use disorder
- Medical illness that can affect brain function
- Past or present history of cardiovascular disease or high blood pressure
- Any history of epilepsy or a known history of seizure disorder
- A history of metal in the head or chest area (except dental fillings or braces)
- Current consumption of psychiatric medication
- Any other medical, neurological or neurosurgical condition that would preclude the administration of repetitive transmagnetic stimulation
The study team makes the final eligibility decision.
Where it is enrolling
- Portland, Oregon, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Portland, Oregon, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.