Kidney Failure, Chronic study: Liberal phosphate target vs Intensive phosphate target
Official title Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)
ClinicalTrials.gov ID: NCT03573089
What this study is testing
What is Liberal phosphate target?
Liberal phosphate target is an investigational medicine, being studied as a potential treatment for kidney failure, chronic.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study wants to find out if keeping blood phosphate levels lower reduces the risk of death or heart problems. It also checks if this approach improves physical health and is a good use of money.
- Who it's for
- People with end-stage kidney disease who have high levels of phosphate in their blood.
- What's involved
- Participants will be assigned to either a group that aims for lower phosphate levels or a group that allows higher levels. They will receive standard care and be monitored for health outcomes.
- Time commitment
- The source text does not specify the duration or visit schedule for this trial.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age ≥45 years, or Age ≥18 years with diabetes,
- ESKD on haemodialysis or peritoneal dialysis, for at least 3 months,
- Currently prescribed at least one phosphate-lowering medication at any dose
- Able to provide informed consent
You likely can't join if
- Elective kidney transplantation scheduled,
- Concomitant major illness / comorbidity that may result in death in the next 6 months in the view of the treating physician,
- Participation in an treatment study that is likely to affect serum phosphate concentration.
The study team makes the final eligibility decision.
Where it is enrolling
- Ubá, Minas Gerais, Brazil
- Ponta Grossa, Paraná, Brazil
- Campina Grande, Paraíba, Brazil
- Porto Alegre, Rio Grande do Sul, Brazil
- Barro Preto, Brazil
- São Paulo, Brazil
- Calgary, Alberta, Canada
- Edmonton, Alberta, Canada
- Vancouver, British Columbia, Canada
- Winnipeg, Manitoba, Canada
- Halifax, Nova Scotia, Canada
- Kingston, Ontario, Canada
- London, Ontario, Canada
- North York, Ontario, Canada
- Oakville, Ontario, Canada
- Orillia, Ontario, Canada
- Oshawa, Ontario, Canada
- Ottawa, Ontario, Canada
- Richmond Hill, Ontario, Canada
- Scarborough Village, Ontario, Canada
+ 58 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Ubá, Minas Gerais, Brazil; Ponta Grossa, Paraná, Brazil; Campina Grande, Paraíba, Brazil; Porto Alegre, Rio Grande do Sul, Brazil; Barro Preto, Brazil; São Paulo, Brazil and 72 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.