Myocardial Ischemia study: Day Light vs ICU Intense Light
Official title Bright Light Exposure in Surgical Patients
ClinicalTrials.gov ID: NCT03822949
What this study is testing
- What it's testing
- The study wants to know whether intense light exposure before cardiac surgery can stabilize a protein called Per2, lower heart‑damage markers, and improve blood‑vessel function in critically ill patients.
- Who it's for
- Adults who are scheduled for heart surgery or who are in the intensive care unit with a serious illness.
- What's involved
- Participants will sit in a bright‑light room for a short period before surgery, give cheek swabs, blood samples, and a tiny piece of heart tissue that would otherwise be discarded, and have routine medical tests.
- Time commitment
- The study lasts a few days around the surgery with a few clinic visits for light exposure and sample collection.
You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 90
You may be able to join if
- Patients undergoing primary sternotomy cardiac surgery
- people in the range of 18 - 90 years old .
- Patient need to be in sinus rhythm at the time of surgery.
You likely can't join if
- patients \ 90 years old
- participation in other clinical trials within the previous 30 days
- pregnancy
- neurological conditions that could impair weaning from ventilator support
- significant CNS disorders or comorbid irreversible conditions with a six-month mortality rate more than 50 percent
- prisoners, or people with altered capabilities to make decision will be enrolled
See the full eligibility criteria
- Patients undergoing primary sternotomy cardiac surgery
- people in the range of 18 - 90 years old .
- Patient need to be in sinus rhythm at the time of surgery.
- patients \ 90 years old
- participation in other clinical trials within the previous 30 days
- pregnancy
- neurological conditions that could impair weaning from ventilator support
- significant CNS disorders or comorbid irreversible conditions with a six-month mortality rate more than 50 percent
- prisoners, or people with altered capabilities to make decision will be enrolled
- medical history of type 2 diabetes
- patients with atrial fibrillation or use of class III anti-arhythmic drug
- patients with a left ventricle ejection fraction \< 40%
- patient in emergency condition
The study team makes the final eligibility decision.
Where it is enrolling
- Denver, Colorado, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 90 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Denver, Colorado, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.