Sleep Apnea study: Oxytocin
Official title Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine
ClinicalTrials.gov ID: NCT03860233
What this study is testing
What is Oxytocin?
an investigational intranasal spray being studied as a potential treatment to lower CPAP pressure needs in sleep apnea. is designed to bind oxytocin receptors and may influence airway muscle tone and breathing regulation.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study wants to find out whether an oxytocin nose spray can reduce the pressure needed from a CPAP machine and lessen low‑oxygen effects during sleep.
- Who it's for
- Adults who have obstructive sleep apnea and already use a CPAP machine.
- What's involved
- You will spray oxytocin into your nose each night, use your CPAP at home for 35 nights, and stay three nights in a sleep lab for monitoring. There is no cost or payment.
- Time commitment
- The study lasts 35 nights total and includes three overnight visits to the sleep lab.
- Phase 1: an early, usually small safety study
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Men or women 18 years of age or older.
You likely can't join if
- people not willing to or otherwise unable to use CPAP for treatment of OSA.
- Presence of other sleep disorders
- Pregnant or breastfeeding women
- Women of child-bearing age (WOCBA) not willing or unable to use an accepted method to avoid pregnancy for the entire duration of the study
- Prisoners or people who are involuntarily incarcerated
- people who are compulsorily detain or treatment of either a psychiatric or physical (i.e. infectious disease) illness
See the full eligibility criteria
- Men or women 18 years of age or older.
- people not willing to or otherwise unable to use CPAP for treatment of OSA.
- Presence of other sleep disorders
- Pregnant or breastfeeding women
- Women of child-bearing age (WOCBA) not willing or unable to use an accepted method to avoid pregnancy for the entire duration of the study
- Prisoners or people who are involuntarily incarcerated
- people who are compulsorily detain or treatment of either a psychiatric or physical (i.e. infectious disease) illness
- Patients unable to give consent because of a language barrier, or other reason.
The study team makes the final eligibility decision.
Where it is enrolling
- Washington D.C., District of Columbia, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Washington D.C., District of Columbia, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.