Clinical trial for Critical Limb Ischemia
Official title FAZA PET/MRI in CLI Patients Pre and Post Revascularization
ClinicalTrials.gov ID: NCT04054609
What this study is testing
- What it's testing
- The study wants to see if the PET/MRI scan can show where and how much tissue is low in oxygen in patients with critical limb ischemia, and whether this information can predict how well patients do after endovascular treatment.
- Who it's for
- Adults who have critical limb ischemia and are scheduled for endovascular revascularization.
- What's involved
- Participants will have a PET/MRI scan using the FAZA tracer before and after their revascularization procedure. The scan will look for areas of low oxygen in the leg tissues.
- Time commitment
- The study lasts about a few weeks, with scans performed before the procedure and again after the procedure, plus any routine follow‑up visits required by the treating doctors.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age \>= 18 years;
- Patients with clinical evidence of critical limb ischemia that are candidates for revascularization treatment;
- A negative urine or serum pregnancy test in women of child-bearing age;
- Ability to provide written informed consent to participate in the study.
You likely can't join if
- Contraindication for MR as per current institutional guidelines;
- Inability to lie supine for at least 30 minutes;
- Pregnant or breastfeeding;
- Unable or unwilling to provide informed consent;
- Impending amputation within 6 weeks of presentation;
- Previous metallic hardware in the lower limbs;
See the full eligibility criteria
- Age \>= 18 years;
- Patients with clinical evidence of critical limb ischemia that are candidates for revascularization treatment;
- A negative urine or serum pregnancy test in women of child-bearing age;
- Ability to provide written informed consent to participate in the study.
- Contraindication for MR as per current institutional guidelines;
- Inability to lie supine for at least 30 minutes;
- Pregnant or breastfeeding;
- Unable or unwilling to provide informed consent;
- Impending amputation within 6 weeks of presentation;
- Previous metallic hardware in the lower limbs;
- Unable to have ethanol.
The study team makes the final eligibility decision.
Where it is enrolling
- Toronto, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Toronto, Ontario, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.