Clinical trial for Schizophrenia
Official title CLOZAPINE Response in Biotype-1
ClinicalTrials.gov ID: NCT04580134
What this study is testing
What is clozapine?
an investigational oral medication being studied as a potential treatment for schizophrenia and related psychotic disorders is designed to block dopamine D2 receptors and modulate serotonin receptors
Also referred to as Clozaril.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study aims to find out how clozapine affects biological measures compared to risperidone in people with psychosis.
- Who it's for
- Adults diagnosed with schizophrenia, schizoaffective disorder, or bipolar I disorder with psychotic symptoms.
- What's involved
- Participants are randomly assigned, without knowing which drug they get, to take either clozapine or risperidone and will have regular clinic visits and medical tests.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60
You may be able to join if
- 18-60y/o; males and females; all races and ethnicities; able to provide written informed consent; able to read, speak, and understand English...
You likely can't join if
- premorbid intellectual ability estimate below 70 (WRAT-4, Word Reading subtest, age-corrected standardized score); comorbid DSM-IV diagnosis of...
The study team makes the final eligibility decision.
Where it's taking place
- Hartford, Connecticut, United States
- Athens, Georgia, United States
- Chicago, Illinois, United States
- Boston, Massachusetts, United States
- Dallas, Texas, United States
Compensation & support
A stipend or payment for your time may be offered.
No amount is published here - ClinicalTrials.gov has no reliable field for payment or travel support. Ask the study team what's actually covered (payment for your time, travel, parking, or other study costs), and never join a trial for the compensation alone.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hartford, Connecticut, United States; Athens, Georgia, United States; Chicago, Illinois, United States; Boston, Massachusetts, United States; Dallas, Texas, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.