Thyroid Gland Carcinoma study: Hyperpolarized Carbon C vs Magnetic Resonance Imaging
Official title An Investigational Scan (hpMRI) for Monitoring Treatment Response in Patients With Thyroid Cancer and Other Malignancies of the Head and Neck Undergoing Radiation Therapy and/or Systemic Therapy
ClinicalTrials.gov ID: NCT04589624
What this study is testing
What is Hyperpolarized Carbon C 13 Pyruvate?
An investigational intravenous agent being studied for use in hyperpolarized magnetic resonance imaging to help predict treatment response in thyroid cancer and other head and neck malignancies.
Also referred to as Hyperpolarized 13C-Pyruvate.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study wants to find out whether a special MRI scan called hyperpolarized MRI can tell doctors early if the cancer is responding to therapy.
- Who it's for
- It is looking for adults who have thyroid cancer or other head and neck cancers and are about to receive radiation or other treatments before surgery.
- What's involved
- Participants will have the special MRI scan, which uses a contrast agent, and may also have other routine tests and visits as part of their treatment plan.
- Time commitment
- The study lasts for the period of the treatment and includes the MRI scan and any scheduled follow‑up visits during that time.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older. Healthy volunteers may be eligible.
You may be able to join if
- Be willing and able to provide informed consent
- Be informed of the investigational nature of this study
- Be diagnosed with thyroid cancer and other malignancies of the head and neck with intent for treatment
You likely can't join if
- Have a history of severe claustrophobia
- Have electrically, magnetically or mechanically activated implants that would preclude magnetic resonance imaging (MRI)
- Have a history of cardiac arrhythmia
- Have an allergy to Gadavist intravenous contrast
- Estimated glomerular filtration rate (eGFR) \< 30
- If female, be pregnant or breast feeding at time of consent
The study team makes the final eligibility decision.
Where it is enrolling
- Houston, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Houston, Texas, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.