Clinical trial for Parkinson Disease
Official title Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment
ClinicalTrials.gov ID: NCT04715984
What this study is testing
- What it's testing
- The researchers want to learn how brain signals in corticostriatal areas relate to non‑motor symptoms, especially cognitive impairment, in Parkinson’s disease.
- Who it's for
- People with Parkinson’s disease who are scheduled for deep brain stimulation surgery.
- What's involved
- During the surgery, electrodes will record brain activity while the patient is awake. No extra medication or treatment is given.
- Time commitment
- The study takes place during the single surgery visit; no additional follow‑up visits are required.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 and older
You may be able to join if
- Scheduled to undergo deep brain stimulation surgery under local anesthesia at Vanderbilt University Medical Center
- Planned clinical electrode trajectory that contacts caudate
- Age greater than or equal to 40
- Diagnosis of Parkinson's disease
- Able to participate in intraoperative testing
You likely can't join if
- Age less than 40
- Not able to participate in intraoperative testing (for example unable to comprehend instructions or follow directions)
- Movement disorder other than Parkinson's disease
See the full eligibility criteria
- Scheduled to undergo deep brain stimulation surgery under local anesthesia at Vanderbilt University Medical Center
- Planned clinical electrode trajectory that contacts caudate
- Age greater than or equal to 40
- Diagnosis of Parkinson's disease
- Able to participate in intraoperative testing
- English speaking
- Age less than 40
- Not able to participate in intraoperative testing (for example unable to comprehend instructions or follow directions)
- Movement disorder other than Parkinson's disease
The study team makes the final eligibility decision.
Where it is enrolling
- Nashville, Tennessee, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Nashville, Tennessee, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.