Obesity study: Exercise
Official title Exercise Effects on Adipose Tissue Structure and Function
ClinicalTrials.gov ID: NCT04812314
What this study is testing
- What it's testing
- The study aims to see if adding exercise to a 10% weight‑loss program affects the structure and function of fat tissue, and whether these changes persist when weight is partially regained.
- Who it's for
- Adults who are overweight or have metabolic syndrome, insulin resistance, or related conditions.
- What's involved
- Participants will have metabolic tests before and after a 10% weight‑loss program, either with or without exercise. Afterward, they will follow a high‑calorie diet to regain half of the lost weight, followed by the same tests again.
- Time commitment
- The study will last several months, with multiple clinic visits for tests and diet periods.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 40
You may be able to join if
- Age: 18-40
- Body Mass Index: 27-45 kg/m2
- No regularly planned exercise/physical activity for at least 6 months
- Women must have regularly occurring menses and must be premenopausal
You likely can't join if
- Evidence/history of cardiovascular or metabolic disease
- Medications known to affect lipid or glucose metabolism, or inflammation
- Weight instability ≥ ± 6 pounds in the last 3 months
- Tobacco or e-cigarette users
- Women must not be pregnant or actively lactating
The study team makes the final eligibility decision.
Where it is enrolling
- Ann Arbor, Michigan, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 40 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Ann Arbor, Michigan, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.