Hypertension study: Neuropeptide Y
Official title Sympathetic Transduction in Obesity-associated Hypertension (OB-HTN)
ClinicalTrials.gov ID: NCT04838678
What this study is testing
What is Neuropeptide Y?
This is an investigational substance being studied to understand how the nervous system affects blood pressure in people with high blood pressure. is designed to be infused into an artery to help researchers measure how the body's stress response changes blood flow and vessel tightness.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether stress changes how the nervous system talks to blood vessels in people with high blood pressure and obesity.
- Who it's for
- You may be able to join if you have high blood pressure and are overweight or obese.
- What's involved
- You will have tests that measure nervous system activity and blood flow while you breathe hard, exercise, or breathe low oxygen. You may also receive small drug injections that widen or tighten blood vessels.
- Time commitment
- The study lasts a few days and includes several visits for tests and drug injections.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 55. Healthy volunteers may be eligible.
You may be able to join if
- Control - BMI\<30, age 18-55
- Hypertensive - BMI\ 30, age 18-55 Obese-hypertensive- BMI\>30, age 18-55, diagnosis of hypertension by 24-hour ambulatory blood pressure monitoring
You likely can't join if
- All groups - presence of other significant cardiovascular disease, renal disease, history of smoking, diabetes,
The study team makes the final eligibility decision.
Where it is enrolling
- Dallas, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 55 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Dallas, Texas, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.