Clinical trial for Breast Cancer
Official title Evaluating Harms and Benefits of Endocrine Therapy in Patients ≥70 Years of Age With Lower Risk Breast Cancer
ClinicalTrials.gov ID: NCT04921137
What this study is testing
- What it's testing
- The trial will compare outcomes for patients who receive hormone therapy versus those who do not, to determine if skipping the therapy is safe and effective for older women with low‑risk breast cancer.
- Who it's for
- Women 70 years or older who have had surgery for early‑stage, hormone‑receptor positive breast cancer that is small and low‑grade.
- What's involved
- Participants will be randomly assigned to either take standard hormone therapy for five years or to stop the therapy. They will have regular check‑ups, blood tests, and imaging to monitor their health and cancer status.
- Time commitment
- The study lasts about five years, with visits every few months for monitoring and follow‑up.
- Phase 4: studies an already-approved treatment
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 70 and older
You may be able to join if
- New invasive estrogen and/or progesterone receptor-positive (ER+ and/or PR+), HER2-negative (HER2-) invasive breast carcinoma diagnosis as per...
- The primary tumour characteristics are either: Grade 1 and ≤3 cm on microscope exam, OR Grade 2 and ≤2 cm on microscope exam, OR Grade 3 and ≤1 cm on...
- Treated with standard loco-regional therapy: breast conserving surgery followed by adjuvant radiotherapy OR total mastectomy
- Axillary node-negative (cN0 or pN0)
- Able to provide oral consent and complete questionnaires in French or English as per study protocol
You likely can't join if
- Metastatic cancer
The study team makes the final eligibility decision.
Where it is enrolling
- Ottawa, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 70 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Ottawa, Ontario, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.