Recruiting at 1 site No phase Parkinson Disease

Parkinson Disease study: Subcortical Stimulation

Official title Motor Network Physiology

ClinicalTrials.gov ID: NCT04957095

What this study is testing

What is Apomorphine Injectable Solution?

An investigational injectable medicine being studied as a potential treatment for Parkinson disease. It is designed to stimulate dopamine receptors in the brain, helping to improve movement control.

Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
This study is looking at how brain networks work in Parkinson’s disease and essential tremor and how deep‑brain stimulation changes them.
Who it's for
You may be able to join if you have Parkinson’s disease or essential tremor and are having deep‑brain stimulation surgery.
What's involved
During your surgery, doctors will record brain activity and may give small electric pulses to the brain. They will also note how you move and feel.
Time commitment
The testing happens during the surgery and does not add extra visits.

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 to 89

You may be able to join if

  • Diagnosis of Parkinson's disease who have been recommended to undergo deep brain stimulation for management of their movement disorder
  • Preoperative MRI without evidence of cortical or subdural adhesions or vascular abnormalities
  • Willingness and ability to cooperate during conscious operative procedure for up to 40 minutes

You likely can't join if

  • Patients with recent use (within one week) of anticoagulant or antiplatelet agents
  • Neurocognitive testing indicating amnestic cognitive deficits

The study team makes the final eligibility decision.

Where it is enrolling

  • Dallas, Texas, United States

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years to 89 years. The study team makes the final eligibility decision.

Where is this trial taking place?

This study is enrolling now at Dallas, Texas, United States. Enter your location above to see the nearest enrolling site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.