Clinical trial for Schizophrenia
Official title Enhancing Prefrontal Oscillations and Working Memory in Early-course Schizophrenia
ClinicalTrials.gov ID: NCT05102929
What this study is testing
- What it's testing
- This study is testing whether intermittent Theta Burst Stimulation can raise brain wave activity in the prefrontal area. It also looks at whether this change improves working memory in early-course schizophrenia.
- Who it's for
- You may be able to join if you have early-course schizophrenia and are willing to try brain stimulation.
- What's involved
- You will receive either real or pretend brain stimulation on the scalp. After each session, your brain waves will be measured with a small sensor. You will also do a memory test.
- Time commitment
- The study lasts a few weeks, with several visits for stimulation, brain wave recordings, and memory tests.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 40
You may be able to join if
- ages 18-40 years
- DSM diagnoses of Schizophrenia Spectrum Axis I disorders
- a duration of less than three years from beginning of psychosis, defined by report of symptoms and/or history of treatment, based on clinical...
You likely can't join if
- DSM intellectual developmental disorder
- significant head injury
- medical illness affecting brain structure or function
- significant neurologic disorder (e.g. seizure disorder)
- personal history or family history of epilepsy
- inability to provide informed consent
See the full eligibility criteria
- ages 18-40 years
- DSM diagnoses of Schizophrenia Spectrum Axis I disorders
- a duration of less than three years from beginning of psychosis, defined by report of symptoms and/or history of treatment, based on clinical guidelines employed in our UPMC psychoses clinics in Pittsburgh.
- DSM intellectual developmental disorder
- significant head injury
- medical illness affecting brain structure or function
- significant neurologic disorder (e.g. seizure disorder)
- personal history or family history of epilepsy
- inability to provide informed consent
- concussion with loss of consciousness (LOC) greater than 10 minutes
- history of electroconvulsive therapy
- diabetes with associated seizures, loss of sensation/weakness in arms or legs, or momentary LOC
- pregnancy or postpartum (\<6 weeks after delivery or miscarriage), as determined by self-report
- a psychotic illness with a temporal relation to substance use or head injury.
- current or past co-morbidity for alcohol or psychoactive substance dependence
- substance abuse, other than cannabis and/or alcohol, within the past one year
The study team makes the final eligibility decision.
Where it is enrolling
- Pittsburgh, Pennsylvania, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 40 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Pittsburgh, Pennsylvania, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.