Clinical trial for Atrial Fibrillation
Official title QOL Improvement After Cardioversion of Persistent AF (QOL-CAFRCT)
ClinicalTrials.gov ID: NCT05136131
What this study is testing
- What it's testing
- This study is testing whether a shock to reset your heart rhythm improves your quality of life. It compares this to a pretend treatment with no medicine.
- Who it's for
- You may be able to join if you have a type of irregular heart rhythm called atrial fibrillation.
- What's involved
- You would get a shock to reset your heart rhythm. Some people get a pretend treatment instead. Neither you nor the team knows which one you get.
- Time commitment
- The study lasts long enough to see if your daily life improves after the treatment.
You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Patients age ≥ 18 years
- Persistent atrial fibrillation
- Unknown symptom burden related to AF
You likely can't join if
- Known left-atrial appendage thrombus
- Prior catheter or surgical ablation for AF
- Intolerance or contraindication to Amiodarone
- Contraindication to appropriate anticoagulation
- Patient is included in another assigned by chance clinical trial
- Patient is unable or unwilling to provide informed consent
See the full eligibility criteria
- Patients age ≥ 18 years
- Persistent atrial fibrillation
- Unknown symptom burden related to AF
- Known left-atrial appendage thrombus
- Prior catheter or surgical ablation for AF
- Intolerance or contraindication to Amiodarone
- Contraindication to appropriate anticoagulation
- Patient is included in another assigned by chance clinical trial
- Patient is unable or unwilling to provide informed consent
- Patient with a history of noncompliance with medical therapy
- Patient does not meet all of the above listed inclusion criteria
- Pregnancy (all women of child bearing age and potential will have a negative BHCG test before enrolment)
- Breastfeeding
- Patients for whom the investigator believes that the trial is not in the interest of the patient
The study team makes the final eligibility decision.
Where it is enrolling
- Newmarket, Ontario, Canada
- Ottawa, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Newmarket, Ontario, Canada; Ottawa, Ontario, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.