Clinical trial for Post Traumatic Stress Disorder
Official title OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit
ClinicalTrials.gov ID: NCT05156112
What this study is testing
- What it's testing
- The study wants to see if treating obstructive sleep apnea with positive airway pressure improves daily functioning, substance‑use outcomes, and PTSD symptoms compared with not treating it right away.
- Who it's for
- Veterans who are living in a residential treatment unit and have diagnosed obstructive sleep apnea, substance use disorder and post‑traumatic stress disorder.
- What's involved
- Participants will be fitted with a positive airway pressure machine and receive instructions on its use while staying in the residential unit; a comparable group will wait for treatment. Both groups continue their usual SUD/PTSD care.
- Time commitment
- The study runs for the length of the residential stay, with regular check‑ins and device monitoring during that time.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- a Veteran of the U.S. military or Reserve/National Guard member
- have an Apnea Hypopnea Index (AHI) 5 per hour
- experienced trauma that occurred in childhood or adulthood; at least one month post-trauma
- have current DSM-5 diagnoses of substance use disorder (SUD) via Structured Clinical Interview for DSM-Substance Use Disorders (SCID-SUD) module with...
- Full post-traumatic stress disorder (PTSD) diagnosis via clinician administered post-traumatic stress disorder (PTSD) scale
You likely can't join if
- have central sleep apnea (Apnea Hypopnea Index (AHI)\>=5 and \> 50% central apneas)
- arrives on the Substance Abuse Residential Rehabilitation Treatment Program (SARRPT) unit already using a positive airway pressure (PAP) device...
- the Substance Abuse Residential Rehabilitation Treatment Program (SARRPT) medical staff advises against the study based on medical history and...
- history of psychosis or mania independent of substance use will be excluded because the presence of these disorders can impede therapy progress
See the full eligibility criteria
- a Veteran of the U.S. military or Reserve/National Guard member
- have an Apnea Hypopnea Index (AHI) 5 per hour
- experienced trauma that occurred in childhood or adulthood; at least one month post-trauma
- have current DSM-5 diagnoses of substance use disorder (SUD) via Structured Clinical Interview for DSM-Substance Use Disorders (SCID-SUD) module with a minimum 20 days of substance use in the last 90 days (Timeline...
- Full post-traumatic stress disorder (PTSD) diagnosis via clinician administered post-traumatic stress disorder (PTSD) scale
- are literate in English
- are on the post-traumatic stress disorder (PTSD) track of the Substance Abuse Residential Rehabilitation Treatment Program (SARRPT) unit
- are capable of giving informed consent
- have central sleep apnea (Apnea Hypopnea Index (AHI)\>=5 and \> 50% central apneas)
- arrives on the Substance Abuse Residential Rehabilitation Treatment Program (SARRPT) unit already using a positive airway pressure (PAP) device (Veteran's previously diagnosed with OSA, but not using positive airway...
- the Substance Abuse Residential Rehabilitation Treatment Program (SARRPT) medical staff advises against the study based on medical history and physical examination
- history of psychosis or mania independent of substance use will be excluded because the presence of these disorders can impede therapy progress
The study team makes the final eligibility decision.
Where it is enrolling
- San Diego, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at San Diego, California, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.