Clinical trial for Right Bundle-Branch Block
Official title His-Bundle Corrective Pacing in Heart Failure
ClinicalTrials.gov ID: NCT05265520
What this study is testing
- What it's testing
- The study compares His‑bundle pacing with standard cardiac resynchronization therapy to see if it works better and how it helps heart function.
- Who it's for
- Adults with heart failure and a right bundle‑branch block who can receive a pacemaker.
- What's involved
- Participants will receive a pacemaker that uses either the new His‑bundle pacing or the standard therapy, and will have follow‑up visits and heart tests.
- Time commitment
- The study lasts about a year, with several clinic visits and heart‑monitoring tests during that time.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age 18 years or older (no upper age limit)
- Optimal medical therapy for heart failure by current guidelines
- New York Heart Association (NYHA) class II HF symptoms, LVEF ≤ 30% and QRS≥ 150 ms (IIb); OR
- NYHA class III-IV a HF, LVEF ≤ 35%, and QRS duration ≥ 150 ms (IIa); OR
- NYHA class III-IV a HF, LVEF ≤ 35%, and QRS duration 120-149 ms (IIb)
You likely can't join if
- Unable to obtain most recent imaging data from echocardiogram within 1 year prior to date of randomization
- Left bundle branch block (LBBB) or intraventricular conduction delay (IVCD) ECG morphology
- Unable or unwilling to follow study protocol
- Less than 12 months life expectancy at consent
- Pregnancy or planned pregnancy during duration of the study
- On heart transplant list or likely to undergo heart transplant
The study team makes the final eligibility decision.
Where it is enrolling
- Phoenix, Arizona, United States
- Los Angeles, California, United States
- Tampa, Florida, United States
- Chicago, Illinois, United States
- Ridgewood, New Jersey, United States
- New York, New York, United States
- Asheville, North Carolina, United States
- Philadelphia, Pennsylvania, United States
- Wilkes-Barre, Pennsylvania, United States
- Burlington, Vermont, United States
- Richmond, Virginia, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Phoenix, Arizona, United States; Los Angeles, California, United States; Tampa, Florida, United States; Chicago, Illinois, United States; Ridgewood, New Jersey, United States; New York, New York, United States and 5 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.