Clinical trial for Rheumatoid Arthritis
Official title Stand UP to Rheumatoid Arthritis (SUPRA)
ClinicalTrials.gov ID: NCT05305066
What this study is testing
What is TNFi?
This is an investigational group of injectable medicines being studied to treat rheumatoid arthritis. It is designed to block a protein called TNF that causes inflammation in the joints.
Also referred to as Etanercept, Adalimumab, Golimumab, Certolizumab.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study aims to find ways to identify the right drug for the right patient at the right time.
- Who it's for
- The study is looking for people with rheumatoid arthritis, a condition that causes joint pain and swelling.
- What's involved
- The source text does not specify the exact treatments, visits, or tests involved.
- Time commitment
- The source text does not specify how long the study lasts or what visits are needed.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age ≥ 18 years;
- Arthritis that fulfills the 2010 ACR/EULAR classification criteria for RA;
- Failure to standard conventional synthetic DMARDs and eligible for second-line b/tsDMARDs (Sub-study 1) or failure to at least one TNF inhibitor and...
You likely can't join if
- Prior b/tsDMARDs for Sub-study 1 or prior b/tsDMARDs other than TNF inhibitors for Sub-study 2;
- Contraindication to b/tsDMARD therapy, such as active infection or untreated latent TB, current malignancy, severe organ dysfunction, history of VTE...
- Overlap with another inflammatory disease requiring specific immunosuppressive therapy, such as lupus nephritis;
- Unable to provide consent or complete forms (alone or with assistance) in English or French
The study team makes the final eligibility decision.
Where it is enrolling
- Montreal, Quebec, Canada
Compensation & support
A stipend or payment for your time may be offered.
No amount is published here because ClinicalTrials.gov has no reliable field for payment or travel support. Ask the study team what's actually covered (payment for your time, travel, parking, or other study costs), and never join a trial for the compensation alone.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team, so confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Montreal, Quebec, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.