Parkinson Disease study: STN DBS - Theta Burst vs STN DBS - Gamma
Official title Evaluation of Neurocognitive Changes in Parkinson's Disease After Low Frequency Burst Stimulation
ClinicalTrials.gov ID: NCT05307055
What this study is testing
- What it's testing
- The study wants to find out whether changing the brain‑stimulator settings can improve cognition in people with Parkinson's disease.
- Who it's for
- People with Parkinson's disease who already have a deep brain stimulator implanted.
- What's involved
- Participants will have their stimulator settings changed in a randomized, double‑blind crossover, complete cognitive tests, and undergo brain MRI scans at the start, week 15, and week 27.
- Time commitment
- The study lasts about 27 weeks and includes several visits for stimulation changes and MRI scans.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Male or female patients who had previously undergone bilateral STN deep brain stimulation implantation
- Age \>18 years old
- Stable medication regimen for at least 3 months.
- Patient informed and able to give written consent
- Able to comply with all testing, follow-ups and study appointments and protocols
You likely can't join if
- History of epilepsy or seizure
- History of dementia
- History of major substance abuse
The study team makes the final eligibility decision.
Where it is enrolling
- Los Angeles, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Los Angeles, California, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.