PTSD study: TF-CBT vs TAU
Official title Neural Connectivity During Therapy for Adolescent PTSD
ClinicalTrials.gov ID: NCT05423444
What this study is testing
- What it's testing
- This study is testing whether different parts of therapy change brain activity in teens with PTSD.
- Who it's for
- You may be able to join if you are a teen with PTSD and can attend therapy sessions.
- What's involved
- You will have brain scans before, during, and after therapy to see how your brain changes. You will also attend regular therapy sessions.
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 12 to 17
You may be able to join if
- ages 12-17 and Tanner stage 2 or above
- history of interpersonal trauma
- PTSD symptoms with a rating of '2' or higher on at least one symptom from each of the 4 clusters, using the Clinician-Administered PTSD Scale for...
You likely can't join if
- current or past use of psychiatric medications
- severe suicidal/homicidal ideation
- current hospitalization
- other current psychotherapy or previous treatment with TF-CBT
- history of head injury with loss of consciousness for \>5 minutes
- IQ\<85
See the full eligibility criteria
- ages 12-17 and Tanner stage 2 or above
- history of interpersonal trauma
- PTSD symptoms with a rating of '2' or higher on at least one symptom from each of the 4 clusters, using the Clinician-Administered PTSD Scale for Children and Adolescents, and having a duration of at least one month
- current or past use of psychiatric medications
- severe suicidal/homicidal ideation
- current hospitalization
- other current psychotherapy or previous treatment with TF-CBT
- history of head injury with loss of consciousness for \>5 minutes
- IQ\<85
- major medical illness
- MRI contraindications (metal in body; braces on teeth)
- psychosis, bipolar 1, autism, developmental disorder, panic disorder
- first-degree family member with diagnosis of psychosis or bipolar I disorder
- substance dependence within the past 3 months or current drug use that is frequent
The study team makes the final eligibility decision.
Where it is enrolling
- San Antonio, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 12 years to 17 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at San Antonio, Texas, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.