PTSD study: Full Prolonged Exposure
Official title Testing Adaptive Interventions to Improve Posttraumatic Stress Disorder Treatment Outcomes in Federally Qualified Health Centers
ClinicalTrials.gov ID: NCT05457985
What this study is testing
- What it's testing
- The study wants to see if beginning with a low‑ or medium‑intensity therapy and then adjusting the treatment after four sessions reduces PTSD symptoms more effectively.
- Who it's for
- Adults who have PTSD and receive care at federally qualified health centers.
- What's involved
- Participants will receive one of two talk‑therapy approaches, attend weekly therapy sessions, and may switch to a different therapy after four sessions if needed, plus complete study questionnaires.
- Time commitment
- The trial runs for several weeks to a few months, with regular therapy visits and assessment appointments.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Receive care at a participating federally qualified health center (FQHC)
- Have a Posttraumatic Stress Disorder checklist (PCL-5) score greater or equal (≥) to 33
- Own a mobile device that can be used for the PTSD Coach App
- Have had psychotropic medication stability for at least 4 weeks
You likely can't join if
- Severe cognitive impairment that in the judgment of the investigators makes it unlikely that the participant can adhere to the study regimen (as...
- High risk of suicide (defined as meeting criteria for Action Step 3 on the Participant Suicide Risk Screening form
- Severe alcohol or substance use disorder (moderate-severe alcohol use disorder on Alcohol Use Disorders Identification Test (AUDIT) (scores ≥ 15) or...
- Active psychosis or unmanaged bipolar disorder
- Unstable housing
- Current engagement in a trauma-focused behavioral treatment (such as Prolonged Exposure or Cognitive Processing Therapy).
See the full eligibility criteria
- Receive care at a participating federally qualified health center (FQHC)
- Have a Posttraumatic Stress Disorder checklist (PCL-5) score greater or equal (≥) to 33
- Own a mobile device that can be used for the PTSD Coach App
- Have had psychotropic medication stability for at least 4 weeks
- Severe cognitive impairment that in the judgment of the investigators makes it unlikely that the participant can adhere to the study regimen (as evidenced by confusion, inability to track discussion or answer questions...
- High risk of suicide (defined as meeting criteria for Action Step 3 on the Participant Suicide Risk Screening form
- Severe alcohol or substance use disorder (moderate-severe alcohol use disorder on Alcohol Use Disorders Identification Test (AUDIT) (scores ≥ 15) or high risk on National Institute on Drug Abuse Quick Screen (scores ≥...
- Active psychosis or unmanaged bipolar disorder
- Unstable housing
- Current engagement in a trauma-focused behavioral treatment (such as Prolonged Exposure or Cognitive Processing Therapy).
- Patients who do not speak English will be excluded for logistical reasons.
The study team makes the final eligibility decision.
Where it is enrolling
- Battle Creek, Michigan, United States
- Flint, Michigan, United States
- Grand Rapids, Michigan, United States
- Houghton Lake, Michigan, United States
- Menominee, Michigan, United States
- Monroe, Michigan, United States
- Sterling, Michigan, United States
- St Louis, Missouri, United States
- Asheville, North Carolina, United States
- Austin, Texas, United States
- Bellingham, Washington, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Battle Creek, Michigan, United States; Flint, Michigan, United States; Grand Rapids, Michigan, United States; Houghton Lake, Michigan, United States; Menominee, Michigan, United States; Monroe, Michigan, United States and 5 more locations. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.