HPV study: Nonavalent HPV vaccine
Official title A Study of Reduced Dosing of the Nonavalent HPV Vaccine in Women Living With HIV
ClinicalTrials.gov ID: NCT05495906
What this study is testing
What is Nonavalent HPV vaccine?
This is an investigational vaccine being studied to see if a reduced dosing schedule works for women living with HIV. It is designed to help the body build immunity against nine types of human papillomavirus (HPV).
Also referred to as Gardasil9.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study aims to find out if a shorter two-dose schedule of the 9-valent HPV vaccine provides the same protection as the standard three-dose schedule for women living with HIV.
- Who it's for
- The study is looking for women aged 18 to 45 who live with HIV and have never received an HPV vaccine before.
- What's involved
- Participants will be randomly assigned to receive either two or three doses of the 9-valent HPV vaccine. They will undergo blood tests to check their immune response and report any side effects.
- Time commitment
- The study lasts for two years and requires participants to visit the clinic for vaccine doses and follow-up tests.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 45, women only. Healthy volunteers may be eligible.
You may be able to join if
- Living with HIV
- Has a uterine cervix
You likely can't join if
- Unable to give fully informed consent
- Pregnant or unwilling to avoid pregnancy during vaccination
- Allergy to the vaccine or its components
- Prior receipt of any HPV vaccine
The study team makes the final eligibility decision.
Where it is enrolling
- Vancouver, British Columbia, Canada
- Toronto, Ontario, Canada
- Montreal, Quebec, Canada
- Québec, Quebec, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 45 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Vancouver, British Columbia, Canada; Toronto, Ontario, Canada; Montreal, Quebec, Canada; Québec, Quebec, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.