Trial studying safety and effects for Posttraumatic Stress Disorder
Official title Mechanisms Underlying the Efficacy of Prolonged Exposure
ClinicalTrials.gov ID: NCT05663151
What this study is testing
- What it's testing
- This study is looking at how your brain and body change during therapy. It aims to find signs that show how well the treatment works.
- Who it's for
- You may be able to join if you have posttraumatic stress disorder (PTSD).
- What's involved
- You would get standard talk therapy for PTSD. You would also take tests to check your brain and body before, during, and after care.
- Time commitment
- The study lasts about 10 weeks with visits at the start, middle, end, and one month later.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 90
You may be able to join if
- a diagnosis of PTSD as defined by DSM-5 (as indicated by meeting diagnostic criteria on the CAPS-5)
- interest in starting PE (as indicated during the informed consent process)
- Veteran
You likely can't join if
- Current or past history of schizophrenic or other psychotic disorders,
- Untreated Bipolar Disorder or a history of a manic/mixed episode within the last 6 months,
- Severe traumatic brain injury,
- Major neurological problems,
- Current substance use disorder,
- Active risk to self or others,
See the full eligibility criteria
- a diagnosis of PTSD as defined by DSM-5 (as indicated by meeting diagnostic criteria on the CAPS-5)
- interest in starting PE (as indicated during the informed consent process)
- Veteran
- Current or past history of schizophrenic or other psychotic disorders,
- Untreated Bipolar Disorder or a history of a manic/mixed episode within the last 6 months,
- Severe traumatic brain injury,
- Major neurological problems,
- Current substance use disorder,
- Active risk to self or others,
- Current participation in cognitive-behavioral therapy,
- Previously received \> 2 sessions of Prolonged Exposure, and
- Having no memory of their traumatic event.
- For participants who are currently prescribed psychotropic medication, they will be eligible for the study provided medication use has been stable for 2 months prior to enrollment and remains stable throughout...
The study team makes the final eligibility decision.
Where it is enrolling
- Boston, Massachusetts, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 90 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Boston, Massachusetts, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.