Trial studying safety and effects for Cystic Fibrosis (CF)
Official title Cystic Fibrosis in the Kidney: Monitoring the Effectiveness of Elexacaftor/tezacaftor/ivacaftor in Urine After a Short Pause of Therapy
ClinicalTrials.gov ID: NCT05818319
What this study is testing
- What it's testing
- The study wants to see if urine bicarbonate levels can show how well the CFTR gene is working and how it changes when ETI treatment is stopped and started again.
- Who it's for
- People with cystic fibrosis who are currently taking the ETI drug combination.
- What's involved
- Participants will have their urine tested for bicarbonate before, during, and after a brief pause in their ETI medication.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adult (age \>17 years) CF patients.
- Normal kidney function estimated by eGFR\>90.
- Adults capable of understanding and voluntarily consenting.
You likely can't join if
- Critical acute illness.
- Severe lung disease (ppFEV1\<40%).
- Adults not capable of understanding and voluntarily consenting.
The study team makes the final eligibility decision.
Where it is enrolling
- Aarhus C, Central Jutland, Denmark
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Aarhus C, Central Jutland, Denmark. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.