Ovarian Endometrioma study: Estetrol/Drospirenone
Official title Estetrol/Drospirenone to Reduce the Average Size of Endometriomas
ClinicalTrials.gov ID: NCT05837624
What this study is testing
What is Estetrol/Drospirenone?
This is an investigational oral pill being studied to see if it can help shrink ovarian endometriomas. It is designed to work by combining two hormones to regulate the menstrual cycle and lower hormone levels that can cause endometriosis tissue to grow.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study aims to find out if taking Estetrol/drospirenone reduces the size of ovarian endometriomas after 3 and 6 months.
- Who it's for
- The study is looking for women aged 18 or older who have an ovarian endometrioma at least 3cm in size and want hormonal treatment.
- What's involved
- Participants will take one pill by mouth every day for 6 months. They will also have ultrasounds and complete questionnaires about their symptoms at the start, 3 months, and 6 months.
- Time commitment
- The study lasts 6 months and requires three hospital visits for tests and check-ups.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older, women only
You may be able to join if
- Equal to or greater than 18 years old
- Has at least one ovarian endometrioma, of at least 3 cm
- Seeking a hormonal treatment for their endometrioma(s)
You likely can't join if
- Any allergy or contraindication to the study drug
- Inability to provide informed consent
- Any hormone use, from the following list, within last 3 months (excluding hormones used for ovarian stimulation for fertility treatments): Estrogen...
The study team makes the final eligibility decision.
Where it is enrolling
- Montreal, Quebec, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Montreal, Quebec, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.