Essential Tremor study: Deep brain stimulation
Official title Coordinated Reset Deep Brain Stimulation for Essential Tremor
ClinicalTrials.gov ID: NCT05897775
What this study is testing
- What it's testing
- The study will see if coordinated reset deep brain stimulation is safe and works short‑term for essential tremor, and will compare its effects to standard deep brain stimulation.
- Who it's for
- Adults who have essential tremor mainly in their arms and are eligible for deep brain stimulation surgery.
- What's involved
- Participants will have a small brain surgery to place electrodes, then receive coordinated reset stimulation and later standard stimulation while doctors monitor tremor and any side effects through visits and tests.
- Time commitment
- The trial involves a short‑term follow‑up over several weeks with multiple clinic visits for programming, monitoring, and assessments.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 and older
You may be able to join if
- Diagnosis of essential tremor (ET)
- Age of 21 or over
- Will be or has been implanted with Boston Scientific Vercise Rechargeable Genus deep brain stimulation (DBS) system
- 7 Tesla (7T) MRI pre-operative scan under Noam Harel PhD's Center for Magnetic Research (University of Minnesota IRB #1210M22183) protocol "Imaging...
- Planned or completed post-operative CT scan
You likely can't join if
- History of musculoskeletal disorders that affect movement of the limbs or gait
- Pregnant women
- Any suspicion of Parkinsonian tremor, including presence of Parkinsonian features such as bradykinesia, rigidity, or postural instability
- Other significant medical disorder (e.g., depression, dementia, or cognitive impairment) that could impede study participation
The study team makes the final eligibility decision.
Where it is enrolling
- Minneapolis, Minnesota, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Minneapolis, Minnesota, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.