Clinical trial for Schizophrenia
Official title Restoring Spindle and Thalamocortical Efficiency in Early-Course Schizophrenia Patients Using Auditory Stimulation
ClinicalTrials.gov ID: NCT05956951
What this study is testing
- What it's testing
- This study is looking at how sleep sounds change brain activity. It also checks if this helps with thinking skills.
- Who it's for
- You may be able to join if you have schizophrenia or a related condition.
- What's involved
- You would sleep in a lab while we play tones. We will check your brain activity and thinking skills.
- Time commitment
- The study involves sleep visits and later check-ins to see how you are doing.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 40. Healthy volunteers may be eligible.
You may be able to join if
- ages 18-40 years
- current DSM-IV defined diagnosis of schizophrenia, schizophreniform or schizoaffective disorder, not drug-induced, with no previously reported...
- duration of ≤5 years from beginning of psychosis, defined by report of symptoms and/or history of treatment according to clinical guidelines employed...
- ages 18-40 years
- no lifetime history of psychiatric disorders
You likely can't join if
- DSM-IV intellectual disability
- significant head injury
- medical illness affecting brain function or structure
- pregnancy or postpartum (\<6 weeks after delivery or miscarriage)
- significant neurological disorder (e.g. seizure disorder)
- inability to provide informed consent
See the full eligibility criteria
- ages 18-40 years
- current DSM-IV defined diagnosis of schizophrenia, schizophreniform or schizoaffective disorder, not drug-induced, with no previously reported psychotic episode
- duration of ≤5 years from beginning of psychosis, defined by report of symptoms and/or history of treatment according to clinical guidelines employed in our University of Pittsburgh Medical Center (UPMC) psychoses...
- ages 18-40 years
- no lifetime history of psychiatric disorders
- no first-degree family history of schizophrenia spectrum disorder or mood disorder with psychotic features.
- DSM-IV intellectual disability
- significant head injury
- medical illness affecting brain function or structure
- pregnancy or postpartum (\<6 weeks after delivery or miscarriage)
- significant neurological disorder (e.g. seizure disorder)
- inability to provide informed consent
- current or past co-morbidity for alcohol or psychoactive substance dependence
- difficult falling and/or staying asleep for more than half the nights of a week, on average
- diagnosis of sleep apnea or restless leg syndrome
- sleeping less than 5 hours or more than 10 hours daily, on average
The study team makes the final eligibility decision.
Where it is enrolling
- Pittsburgh, Pennsylvania, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 40 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Pittsburgh, Pennsylvania, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.