Thumb Osteoarthritis study: Ketorolac vs Triamcinolone
Official title NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis
ClinicalTrials.gov ID: NCT05992883
What this study is testing
What is Ketorolac?
An investigational injection being studied for thumb osteoarthritis.
Also referred to as Toradol.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is testing whether an NSAID injection works better than a steroid injection for thumb arthritis symptoms.
- Who it's for
- You may be able to join if you have moderate to advanced arthritis in the base of your thumb.
- What's involved
- You will receive one of two injections into the thumb joint. The study team will decide which one you get. You will have follow‑up visits to check how you feel.
- Time commitment
- The study lasts a few months, with several visits to receive injections and report your symptoms.
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 and older
You may be able to join if
- Adults \>40 years of age
- Pain at the thumb base brought on by direct pressure (grind test) and with movement
- Pain resistant to previous conservative management (including over the counter medications (ibuprofen/acetaminophen), icing, splinting/braces, or...
- Radiological observation indicative of arthritis based on the Eaton-Littler classification system (stages 1 through 4)
- Patient understands the protocol and signed the informed consent
You likely can't join if
- Known allergy to either of the treatment products
- Patient's analgesic treatment regimen or other modalities of managing symptoms/pain associated with their hand pathology was modified within four...
- Symptomatic Scaphoid-trapezial arthritis present
- Localized or systemic infection
- Previous thumb surgery on study thumb
- Previous thumb injury on study thumb
See the full eligibility criteria
- Adults \>40 years of age
- Pain at the thumb base brought on by direct pressure (grind test) and with movement
- Pain resistant to previous conservative management (including over the counter medications (ibuprofen/acetaminophen), icing, splinting/braces, or topical analgesics)
- Radiological observation indicative of arthritis based on the Eaton-Littler classification system (stages 1 through 4)
- Patient understands the protocol and signed the informed consent
- Patient is covered by health insurance
- Known allergy to either of the treatment products
- Patient's analgesic treatment regimen or other modalities of managing symptoms/pain associated with their hand pathology was modified within four weeks before trial inclusion
- Symptomatic Scaphoid-trapezial arthritis present
- Localized or systemic infection
- Previous thumb surgery on study thumb
- Previous thumb injury on study thumb
- Patient with inflammatory arthritis (e.g., rheumatoid arthritis, psoriatic arthritis)
- Severe and/or uncontrolled hypertension
- De Quervain tendinopathy present
- History of injection to the trapeziometacarpal joint on study thumb within the previous 6 weeks
- Uncontrolled diabetes
- Pregnant or lactating females. Female participants of childbearing potential must have a negative pregnancy test before the injection.
- Immunodeficient patients
- Patients that are currently using nicotine products, or who have quit in the last 12 months
- Patients under guardianship, curatorship, or are otherwise not self-sufficient
- Patients participating in another clinical research trial which interferes with this study protocol or outcomes
- Patients unable to follow the protocol in the investigators' judgement.
The study team makes the final eligibility decision.
Where it is enrolling
- Rochester, Minnesota, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Rochester, Minnesota, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.