Clinical trial for Prostate Cancer
Official title PSMA-Guided Ablation of the Prostate
ClinicalTrials.gov ID: NCT06003556
What this study is testing
- What it's testing
- This study checks if a new type of PET scan is better than standard MRI at finding all cancer spots in the prostate. It aims to see if this leads to fewer cancer leftovers or returns after treatment.
- Who it's for
- Men with prostate cancer on one side of the prostate who are eligible for focused treatment.
- What's involved
- Participants will be randomly assigned to get a PSMA PET scan or no extra imaging. Those with cancer on one side will receive focused treatment (ablation) on that side. Everyone will have scans and biopsies 12 months later.
- Time commitment
- The study involves initial imaging, potential focused treatment, and follow-up scans and biopsies 12 months later.
- Phase 2: a mid-size study of how well it works
Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 and older, men only
You may be able to join if
- Age \> 50
- Clinical stage \< T2b
- PSA \< 15
- Combined targeted and systematic MRI-guided biopsy shows unilateral Gleason Grade Group 2 or 3 prostate cancer
You likely can't join if
- Unable to obtain consent
- Weight \>250 kg (weight limitation of scanners)
- Unable to lie flat for 30 minutes to complete the PET imaging
- Lack of intravenous access
- eGFR \< 40 mL/min/1.73 m2 and/or a history of a severe reaction to CT contrast
- Prior androgen deprivation therapy or radiation therapy to prostate gland
The study team makes the final eligibility decision.
Where it is enrolling
- Calgary, Alberta, Canada
- Edmonton, Alberta, Canada
- Toronto, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 50 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Calgary, Alberta, Canada; Edmonton, Alberta, Canada; Toronto, Ontario, Canada. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.