Parkinson Disease study: Neurostimulation vs Carbidopa
Official title Personalized Real-Time DBS and PD Mechanisms
ClinicalTrials.gov ID: NCT06013956
What this study is testing
What is Carbidopa 25/Levodopa 100Mg Tab?
This is an investigational anti-parkinsonian medication being studied to help understand brain activity in Parkinson Disease. It is designed to increase levels of dopamine in the brain to help manage movement symptoms.
Plain-language explanation of the investigational treatment. It is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The study wants to learn how brain activity patterns relate to Parkinson’s motor symptoms and how they can guide future closed‑loop stimulation devices.
- Who it's for
- Adults with Parkinson’s disease who are scheduled for deep brain stimulation surgery.
- What's involved
- Participants will have their brain activity recorded during surgery and while taking medication, and the data will be used to model how stimulation can be adjusted in real time.
- Time commitment
- The study lasts only the period of the surgery and the immediate post‑surgery monitoring; no additional long‑term visits are required.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Ability to provide informed consent.
- Clinical diagnosis of idiopathic Parkinson's disease.
- Determined, as per standard of care, to be a candidate for deep brain stimulation (DBS) surgery targeting the subthalamic nucleus.
- Ability to tolerate delays in taking daily standard Parkinson's disease medications. Key
You likely can't join if
- Secondary Parkinsonism, stroke, or progressive central nervous system disease other than Parkinson's disease.
- Patient has a condition that, in the opinion of the investigators, would significantly increase the risk of interfering with study compliance...
The study team makes the final eligibility decision.
Where it is enrolling
- Cleveland, Ohio, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part, but confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
This study is enrolling now at Cleveland, Ohio, United States. Enter your location above to see the nearest enrolling site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool that is independent of the study sponsor. Details come from ClinicalTrials.gov. The study team decides eligibility, and your own doctor gives medical advice.